"Advanced NMR Spectroscopy" 25/05 - 05/06 & 22/06 - 26/06 (2009) Utrecht/Nijmegen
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Advanced NMR Workshop
"Advanced NMR spectroscopy"
The Bijvoet-IMM Research Alliance (BNRA) organizes from May 25 to June 5, and a third week June 22 to 26, 2009, a course on advanced NMR spectroscopy. The course covers the theoretical aspects of current biomolecular high-resolution NMR spectroscopy and is intended for Ph.D. students and advanced undergraduate students who already have a thorough knowledge of NMR spectroscopy.
The course is organized by the NMR group at the Institute for Molecules and Materials (IMM) at the Radboud University Nijmegen and the NMR research group of the Bijvoet Center for Biomolecular Research at Utrecht University. The course will take three weeks in total and will be given partially in Utrecht and partially in Nijmegen.
Course contents:
The course consists of lectures and practical sessions. Topics will be Product Operator Formalism and important tools/ building
blocks of NMR experiments, e.g. INEPT, HSQC/HMQC, Decoupling, Selective pulses, Phase Coherence Selection, Gradients, TOCSY
and TROSY. The following applications will be addressed: solid state NMR, heteronuclear 3D/4D NMR, triple resonance NMR, NMR
relaxation theory and applications on protein dynamics.
The acquired knowledge will be directly applied in the practical sessions.
Topics & Lecturers:
Basics of Operators and their usage in Quantum Mechanics |
Andres Brinkman |
Product Operator Formalism, theory & practice |
Sybren Wijmenga |
Dipolar couplings (par 2.8 Cavanagh et al) |
Sybren Wijmenga |
NMR Tools |
Geerten Vuister |
Anisotropic interactions Tensors / Rotations |
Marc Baldus |
Coherence Selection & Gradients |
Rolf Boelens / Ruud Scheek |
Heteronuclear 3D/4D NMR / Triple resonance NMR |
Rolf Boelens |
Relaxation theory (chapter 5) |
Klaartje Houben |
Relaxation theory (chapter 8) |
Frans Mulder |
Cross-correlated relaxation |
Marco Tessari |
TROSY, CRINEPT & CRIPT |
Marco Tessari |
Solid-state NMR |
Marc Baldus |
Residual Dipolar Coupling |
Markus Zweckstetter |
Paramagnetic NMR |
Marcellus Ubbink |
Program (pdf):
WEEK 1: May 25 - May 29 (Nijmegen)
Product Operator Formalism and Selected Applications
Time |
Mon May 25 |
Tue May 26 |
Wed May 27 |
Thu May 28 |
Fri May 29 |
10:00-12:30 |
Wijmenga / Brinkman |
Wijmenga |
Wijmenga |
Wijmenga |
Baldus |
12:30-13:30 |
Lunch |
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13:30-17:00 |
Brinkman |
Wijmenga |
Wijmenga |
Vuister |
Baldus |
WEEK 2: June 2 - June 5 (Utrecht)
Coherence, 3D/4D NMR and Relaxation
Time |
Mon June 1 |
Tue June 2 |
Wed June 3 |
Thu June 4 |
Fri June 5 |
10:00-12:30 |
FREE DAY |
Boelens |
Vuister |
Houben |
Boelens |
12:30-13:30 |
Lunch |
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13:30-17:00 |
Scheek |
Vuister |
Houben |
Boelens |
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Tasks for the intervening weeks will involve analysis of pulse sequences
WEEK 3: June 22 - June 26 (Utrecht)
Relaxation, TROSY, Solid State NMR and paramagnetic NMR
Time |
Mon June 22 |
Tue June 23 |
Wed June 24 |
Thu June 25 |
Fri June 26 |
10:00-12:30 |
Mulder |
Tessari |
Baldus |
Zweckstetter |
Ubbink |
12:30-13:30 |
Lunch |
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13:30-17:00 |
Mulder |
Tessari |
Baldus |
Zweckstetter |
Ubbink |
Language: English
Location: The workshop will take place at the NMR Research group in Utrecht and the Department of Physical Chemistry in Nijmegen.
Prerequisite knowledge:
The course is intended for Ph.D. students and advanced undergraduate students (primarily of the participating institutes) who already have a thorough knowledge of NMR spectroscopy.
Further info:
- Prof. Dr. R. Boelens Phone: 030-2534035
Registration
Please send an email to the NMR secretariat (Barbara Hendricx: secr@nmr.chem.uu.nl) and indicate your NMR background. Attach a short CV in your email. International applicants should provide a short recommendation letter by their supervisor.
Participation is free for members of the groups of the Bijvoet-IMM Research Alliance. The registration fee for participants from other universities amounts to Euro 350.- and for others to Euro 1000.-. Participants should cover their own travel and lodging expenses. Deadline for subscription is Tuesday April 28. Applicants will receive an acceptance notice in the first week of May, with information for booking accommodation.