Graduate Course
"Advanced NMR Spectroscopy"
May 21-June 8, 2007, Utrecht-Nijmegen


The Bijvoet-IMM Research Alliance (BNRA) organizes from May 21 to June 8, 2007, a course on advanced NMR spectroscopy. The course covers the theoretical aspects of current biological high-resolution NMR spectroscopy and is intended for Ph.D. students and advanced undergraduate students who already have a thorough knowledge of NMR spectroscopy (at the level of at least R.K. Harris, 'Nuclear Magnetic Resonance Spectroscopy. A physicochemical view', Longman, 1986 or equivalent).

The course is based on the following book (to be bought by those who attend): 'Protein NMR Spectroscopy. Principles and Practice'. by J. Cavanagh, W.J. Fairbrother, A.G. Palmer III, M. Rance and N.J. Skelton., Academic Press, 2nd edition, 2006.

In addition, for Residual Dipolar Couplings, Relaxation, etc. selected parts will be used from 'Multidimensional NMR of Liquids. Basic principles and experimental methods' by F.J.M. van de Ven, Wiley, 1995 and recent literature.

The course is organized by the NMR group at the Institute for Molecules and Materials (IMM) at the Radboud University Nijmegen and the NMR group of the Bijvoet Center for Biomolecular Research at Utrecht University and will be given in three non-consecutive weeks in Utrecht and Nijmegen.

Week 1 21 May-25 May Nijmegen
Week 2 29 May-30 May Nijmegen
  31 May-1 June Utrecht
Week 3 4 June-8 June Utrecht

The course is given between 10.00 am - 16.00 pm. Location to be announced. In addition tasks will be handed out, related to the course material.

Participation is free for members of the groups of the Bijvoet-IMM Research Alliance. The registration fee for participants from other universities amounts to Euro 350.- and for others to Euro 1000.-. The number of participants is limited to 16.

Topics

NMR concepts
Product Operator Formalism
Selected Applications, e.g. residual dipolar couplings.
Various NMR Tools / Building blocks,
e.g. INEPT, HSQC/HMQC, Decoupling, Selective pulses
Phase Coherence Selection
Gradients
Basic 2D NMR, e.g. COSY, E.COSY and TOCSY
Heteronuclear and triple resonance 3D and 4D NMR
NMR relaxation theory
Protein dynamics
TROSY, CRINEPT, CRIPT and applications in protein NMR

Lecturers (provisory list):


Language: English


Prerequisite knowledge:

The course is intended for Ph.D. students and advanced undergraduate students (primarily of the participating institutes) who already have a thorough knowledge of NMR spectroscopy.


Further info:
Registration

For registration send your application, with a short CV, to
Applicants will receive an acceptance notice as soon as possible.


Rolf Boelens, March 2007