Name Mickael KRZEMINSKI Sex Male
Adress Albatrosstraat, 47 bis Nationality French
3582 EV, UTRECHT Date of birth November, 29th 1978
Telephone +31 30 2539932 Marital status Single




Education



2001-2003 Master (Magistère) of Biotechnology:
Third year   Computer Science and Molecular Modeling at Paris VI University
Second year   Cellular Biology at Paris XI University
First year   Biochemistry at Paris XI University
2000 DEUG Life Science at Paris XI University
1998-1999 Medical studies at Paris XI University and Kremlin-Bicêtre
1997 Bachelor speciality : Mathematics, Physic, Chemistry, Biology


Research Experience



Sept. 2004 Beginning of a PhD in the NMR laboratory of the Bijvoet Center, Utrecht (Netherlands)
Study of the partially unfolded states of protein.
2004 Pasteur Institute, Paris, Unité de Bio-Informatique Structurale, under the direction of M. Nilges (3 months)
Translation of the ARIA Simulating Annealing Protocol from CNS into Xplor-NIH and implementation of new methods
2003-2004 Pasteur Institute, Paris, Unité de Bio-Informatique Structurale (10 months)
Modelling of Guanine Nucleotide exchange Factor complexed with GTPase EhRacG from Entamoeba histolytica
2003 Pasteur Institute, Paris, Unité de Bio-Informatique Structurale, under the direction of R. Maroun (6 months)
Prediction of the secondary structure of of the GPI-Mannosyltransferase-I from Entamoeba histolytica
2002 Pasteur Institute, Paris, Unité de Biologie Cellulaire du Parasitisme, under the direction of N. Guillèn (2 months)
Development of a real-time PCR assay for the detection of virulence factors in Entamoeba histolytica
2001 Pasteur Institute, Paris, Unité de Génétique des Biofilms, under the direction J-M. Ghigo (2 months)
Determination of genes responsible of the formation of biofilms in Escherichia coli with a cloning-free gene disruption method (3-Step PCR)


Publications



1. Krzeminski M, Fuentes G, Boelens R, Bonvin AM
MINOES: A new approach to select a representative ensemble of structures in NMR studies of (partially) unfolded states.
Application to Delta25-PYP.

Proteins, 2008 (ahead of print)
2. Weber C, Blazquez S, Marion S, Ausseur C, Vats D, Kzreminski M, Rigothier M-C, Maroun RC, Bhattacharya, Guillén
Bioinformatics and Functionnal Analysis of an Entamoeba histolitica Mannosyltransferase Necessary for Parasite Complement Resistance and Hepatical Infection
PLOS Neglected Tropical Diseases, 2008, 2(51):e165
3. de Vries SJ, van Dijk AD, Krzeminski M, van Dijk M, Thureau A, Hsu V, Wassenaar T, Bonvin AM
HADDOCK versus HADDOCK: new features and performance of HADDOCK2.0 on the CAPRI targets.
Proteins. 2007 Dec 1;69(4):726-33
4. Wu AM, Singh T, Liu JH, Krzeminski M, Russwurm R, Siebert HC, Bonvin AM, André S, Gabius HJ.
Activity-structure correlations in divergent lectin evolution: fine specificity of chicken galectin CG-14 and computational analysis of flexible ligand docking for CG-14 and the closely related CG-16.
Glycobiology. 2007 Feb;17(2):165-84
5. Aguilar-Rojas A, Almaraz-Barrera Mde J, Krzeminski M, Robles-Flores M, Hernandez-Rivas R, Guillen N, Maroun RC, Vargas M.
Entamoeba histolytica: inhibition of cellular functions by overexpression of EhGEF1, a novel Rho/Rac guanine nucleotide exchange factor.
Exp Parasitol. 2005 Mar;109(3):150-62. Epub 2005 Jan 26.
6. Beloin C, Valle J, Latour-Lambert P, Faure P, Kzreminski M, Balestrino D, Haagensen J. A. J, Molin S, Prensier G, Arbeille B and Ghigo J-M.
Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression.
Molecular Microbiology, 2004, 51(3) : 659.674


Languages and Programming



French Mother tongue
English Written, Spoken and Read
Programming languages C, R, Python, CNS, Xplor


Interests



Sport (football, fitness), cinema, reading, informatics