Some protein can exist in different states (Complexed to other proteins, (partially) unfolded,...) NMR experiments, like HSQC
allow us to detect which residues of the protein is involved the biological process. Nevertheless, interpretation of data can be
subjective and misinterpretation can lead to fatal errors.
SAMPLEX (Smoothed Automatic Mapping of Protein from Listed Extremes) is a program that will find from NMR data and without any subjectivity which part of a protein, which exists in two different states, is perturbed.
The algorithm makes use of NMR data and the structure of the protein in the ground state (Unbound and folded). After estimating the probability of each residue to be in a perturbed environment, it will use a topological approach to detect which regions (blocks) of te protein might be involved.
To read more and download SAMPLEX, click here.
SAMPLEX (Smoothed Automatic Mapping of Protein from Listed Extremes) is a program that will find from NMR data and without any subjectivity which part of a protein, which exists in two different states, is perturbed.
The algorithm makes use of NMR data and the structure of the protein in the ground state (Unbound and folded). After estimating the probability of each residue to be in a perturbed environment, it will use a topological approach to detect which regions (blocks) of te protein might be involved.
To read more and download SAMPLEX, click here.
MINOES (MINnimal Optimal Ensemble Selection) aims at selecting a subensemble, which will best fit experimental data, among an
ensemble of generated structures.
To read more and download MINOES, click here.
Solar sytem |
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| This script will show you the four first closest planets to the sun. Only the size of the sun and the moon has not been respected. It is better to have a clean screen to catch sight of stars... |
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Christmas Tree |
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| A wonderful Christmas Tree, with the snow. |
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Dirac |
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| The function used for creating this fancy animation has been based on a Dirac distribution, hence the name! |
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Contagious colors |
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One of the most famous Markov Chain showed: the stepping stone in 3D. You can
change the amount of spheres and colors, and the maximum number of steps.
Moreover, you have the possibility to see the evolution of your system in real time or to minimize this time to get faster the final evolution. |
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PyMolTris |
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One of the most famous game of the world under PyMol. No need to explain the rules anymore.
You can even make use of some fancy jokers to get more points.
Requierement: PyMol 0.99 or more and the Numeric Python library. This version works under Windows, Macintosh and Linux. |
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